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Project title: Imaging molecular dynamics within 3D focal adhesions
This project aims to test the hypothesis that integrins have distinct roles in signaling to the spatial regulation of microtubule and actin cytoskeletons to control adhesion contact dynamics, and persistent migration within 3D ECM environments. The aims are: 1) to use advanced fast confocal and super-resolution microscopy approaches to study the temporal and spatial assembly of focal adhesion components. 2) Using our characte...
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