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Fellowship & Grant details

Fellowship posted by Italian Ministry of Education, University and Research (06/12/2012 02.36)

SYNTHESIS OF BIOLOGICALLY ACTIVE CYCLOPROPANATED COMPOUNDS

Please note that the job is no longer active!

The introduction of a cyclopropane ring into bioactive molecules significantly affects their potency or selectivity through augmented conformational restrictions. In particular two topics, strictly synthetic, will be dealt with in this framework. One concerns the development of a synthetic method for the preparation of aminopipecolic acids having in mind their use as scaffolds for the preparation of new ligands for the integrins. In particular, the synthesis of cyclopropanated aminopipecolic acids around which it will be possible to build some cyclopeptides. The second one deals with the synthesis of cyclopropanated derivatives of fragrances. As very often the allergenicity of the fragrances depends on the presence of unsaturations, the cyclopropanation of these unsaturations will also generate nonallergenic molecules, besides affecting the odour. In this context, the synthesis of some cyclopropanated fragrances structurally close to known fragrances will be realized,

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Research Fields

Chemistry - Organic chemistry


Programme Description
Number of awards per year1
Annual budget22946
Frequency of calls12 mesi
International mobility required ?no
Eligible destination country/ies for fellowsItaly
Eligibility of fellows: country/ies of residenceAll
Eligibility of fellows: nationality/iesAll
Website of Fellowship Programmehttp://www.unifi.it/CMpro-v-p-391.html
Fellowship's Details
Career StageEarly stage researcher or 0-4 yrs (Post graduate)
Research ProfilesNot defined
Employment contract with full social securityyes
Total amount per fellowship per year22946
Currencyeuro
Covers salaryyes
Covers travel and subsistenceno
Covers research costsno
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Application deadline

17/12/2012

Other fellowship details
Fellowship ID

43778

Funding organisation / Contacts
Università di Firenze- Dipartimento di Chimica

Public research
Sesto Fiorentino - Italy
http://www.unifi.it/CMpro-v-p-391.html
E-mails
ricerca@polosci.unifi.itPhones
055/5253858

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