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Current research in the biomedical area is strongly oriented towards the identification of small molecule of non-peptidic nature, which bind to receptors similarly to peptide ligands by mimicking the functional features responsible for bioactivity. The identification of such molecules is important for the generation of new chemical probes with aim to develop new diagnostic agents, and also therapeutics based on the same mechanism of action. This research program will consist of the synthesis of heterocyclic molecules using amino acids and sugar derivatives as precursors, using coupling reactions of peptidomimetic components; development of the process and study of diagnostic and therapeutic applications; validation of selected molecules in biomedical fields of interest. The generation of molecular platforms using the above-described methods will enable the selection of candidate structures for the screening towards biological targets of interest.
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