Fellowship & Grant details

Fellowship posted by Italian Ministry of Education, University and Research (06/12/2012 02.35)

Development of targeted magnetic-optical nano-carrier for the treatment of solid tumors with chemotherapy and hyperthermia.

Please note that the job is no longer active!

The project intends to develop a new pharmaceutical product for the treatment of human solid tumors. This product exploits the ability of hyperthermic and chemiotherapic treatment. In the project magnetic and/or gold nanoparticles will be developed and linked to different targeting units depending on tumor models. The nanoparticles will be loaded with antitumoral drugs.

The selected models are: 1) pancreas adenocarcinoma and esophageal-gastric junction and/or gastric carcinoma using as target hERG (human ether a gògò related gene); 2) head and neck carcinoma using as a target the EGFR.

The research includes evaluation of: cellular uptake of nanoparticles functionalized with and without antitumoral drugs; cell and tissue toxicity in mice; biodistribution by MRI; effects of hyperthermia on in vitro experimental models using indices of vitality and cell proliferation.

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Research Fields

Medical sciences
Biological sciences

Programme Description
Number of awards per year1
Eligible destination country/ies for fellowsItaly
Eligibility of fellows: country/ies of residenceAll
Eligibility of fellows: nationality/iesAll
Website of Fellowship Programme
Fellowship's Details
Career StageMore Experienced researcher or >10 yrs (Senior)
Research ProfilesNot defined
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Funding organisation / Contacts
Università degli Studi di Firenze - Dipartimento di Fisiopatologia Clinica

Public research
Firenze - Italy