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the research project pertains to the development of an analytical strategy in order to identify and quantify pharmaceuticals products in surface waters and wastewaters. The study will focus on the determination of metabolites and by-products after each stage of wastewater treatment process and their fate in the environmental compartments investigated. In particular, attention will be paid on the optimization of the sample preparation, which is a key factor in determining the success of analysis. Solid phase extraction represents the most widely used method, furthermore considering the possible automation of the procedure itself. The detection will be carried out by employing tandem mass spectrometric techniques that, coupled with chromatographic separation, fulfil the performance criteria for the determination of these compounds in environmental matrixes
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