Expression studies of mRNAs in in vitro and in vivo models of neurodegenerative diseases.

The OU Translational Medicine for diagnostics and innovative therapies Nervous System and Cardiopulmonary Laboratory (NeuroTransMed), included activities aimed to optimize the chain for studies of safety and efficacy of novel therapies degenerative diseases of the nervous system, to be offered as a service for preclinical testing of neuroactive molecules on mouse models of disease. Aim of this project is to optimize the expression study of mRNA of interest in in vitro preparation (SY5Y line and primary neurons) by real time PCR (inclusing microdissected samples). Protocols for growth and trophic factor (NGF, BDNF, CNTF, GDNF, VEGF), neuropeptides, neurotransmitter enzymes, apoptosis will be developed, tested and optimized.

Research Fields

Biological sciences - Laboratory animal science

Eligibility criteria

to apply for research grants fill out the form available at the following address: https://www.aric.unibo.it/AssegniRicerca/BandiPubblicati/zz_Bandi_din.aspx

---

Programme Description

Eligible destination country/ies for fellows	Italy
Eligibility of fellows: country/ies of residence	All
Eligibility of fellows: nationality/ies	All
Website of Fellowship Programme	https://www.aric.unibo.it/AssegniRicerca/BandiPubblicati/zz_Bandi_din.aspx

Fellowship's Details

Career Stage	Early stage researcher or 0-4 yrs (Post graduate)
Research Profile	Not defined