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Fellowship & Grant details

Fellowship posted by Italian Ministry of Education, University and Research (04/10/2012 02.51)

Induction of myogenesis as a mean to delay/correct muscle atrophy in experimental cancer cachexia

Please note that the job is no longer active!

Cancer cachexia is a multifactorial syndrome characterized by loss of muscle and adipose tissue that negatively affects both patient quality of life and their tolerance to antineoplastic therapies. While a tissue hypercatabolic response is widely recognized to contribute to the pathogenesis of this syndrome, little is known about the involvement of impaired myogenesis. In this regards, previous results demonstrated that muscle “stem-like” quiescent (satellite) cells accumulate in the skeletal muscle of cachectic tumor-bearing animals (Penna et al., 2010). Aim of the present project is to assess if, in addition to satellite cells, also pericyte-like cells of mesodermic origin (mesoangioblasts) can be recruited to the cachectic muscle. In particular, the study will define the possibility to stress satellite cells and/or mesoangioblast activation and differentiation in order to improve muscle atrophy in experimental cancer cachexia. References: Penna F. et al., PLoS One, 5:e13604, 2010.

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Research Fields

Biological sciences

Other costs

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Eligibility criteria

The call and how to apply are available at the following address: https://www.serviziweb.unito.it/albo_ateneo/

Selection process

qualifications and interview (in Turin)


Programme Description
Number of awards per year1
Eligible destination country/ies for fellowsItaly
Eligibility of fellows: country/ies of residenceAll
Eligibility of fellows: nationality/iesAll
Website of Fellowship Programmehttps://www.serviziweb.unito.it/albo_ateneo/
Fellowship's Details
Career StageEarly stage researcher or 0-4 yrs (Post graduate)
Research ProfilesNot defined
Employment contract with full social securityyes
Total amount per fellowship per year19367
Currencyeuro
Covers salaryyes
Covers travel and subsistenceyes
Covers research costsyes
Maximum duration of fellowship24
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Application deadline

29/11/2012

Other fellowship details
Fellowship ID

39724

Funding organisation / Contacts
Universita' degli Studi di Torino

Public research
Turin - Italy
http://www.unito.it/
E-mails
arearicerca-assegni@unito.it

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