Since end 2008, EPAA has agreed to explore the opportunities that stem cells could play in developing novel approaches for the potential hazard characterization of chemicals and drugs.
A lot of research on stem cells is currently ongoing within the EU and wider area, but it is considered to be value in assessing how such work may fit into an overall strategy for evaluating safety without animal testing. This EPAA project aims at directing the stem cells research towards the industry needs for safety assessment.
In the opinion of the EPAA Platform on Science, the current research on the use of stem cells is suffering from a clear guidance to develop novel testing strategies for safety assessment. The identification of gaps in testing strategies is relevant in order to select the cell types of interest as well as the most appropriate readout to identify mode of actions. This is important for multiple sectors and therefore a good opportunity for EPAA to coordinate this activity.
Workgroup 1 on Fundamental research on Stem Cells
Workgroup 2 on Long term Toxicity