JRC Reference Report: robust methods for GMO detection ready at hand
A new reference report published today by the JRC lists 79 reference methods for GMO analysis which have been validated according to international standards. This compendium, developed jointly by the EU Reference Laboratory for Genetically Modified Food and Feed (EU-RL GMFF) and the European Network of GMO Laboratories (ENGL), presents the technical state of the art in GMO detection methods. Each method is described in a user-friendly way, facilitating the implementation of GMO legislation by official control bodies.
Most of the methods have been developed by the biotechnology industry and validated by the EU-RL GMFF for their applicability according to EU legislation. They will be used by EU Member States to organise official controls on GMOs and the compendium will therefore contribute to the health and consumer protection of European citizens.
The following selection criteria were applied to decide on inclusion of GMO detection methods, which were validated in international collaborative trials during the period 1999 to 2009:
- Considering the largest common denominator in the present global framework of GMO analysis, this first issue of the compendium focuses on Polymerase Chain Reaction (PCR) methods i.e. DNA-based detection methods.
- Compliance with ISO 5725 international standard (accuracy (trueness and precision) of measurement methods and result) and/or the IUPAC (International Union of Pure and Applied Chemistry) “Protocol for the design, conduct and interpretation of method performance studies”.
The 79 reference methods thus identified are described in a short executive summary which provides all essential information. For further details on some of the methods the relevant references are provided. This user-friendly lay-out makes the compendium a practical tool and facilitates implementation of the reference methods by GMO control laboratories.