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The Regulation 45/2001 provides the appointment of a Data Protection Officer (DPO) for every EU Institution and Body. EU Commission has also appointed a DPO since 2001.

The role, mandate and responsibilities of the DPO is to ensure that controllers respect their data protection obligations and data subjects are informed of their rights and obligations pursuant to Regulation 45/2001.

The DPO ensures in an independent manner, the internal application of the provisions of the Regulation 45/2001 and keeps a public Register of the processing operations carried out by the controllers of the Commission.

The European Commission has appointed a Data Protection Coordinator (DPC) in each directorate-general (DG). This has been justified by the size of the institution and the necessity to have relays in the different DGs. There is also a specific DPO for OLAF.