European Inventor Award 2013 - Patrick Couvreur (FRA) - Nano-capsules for targeted delivery of anti-cancer drugs (nominee in the category "Research")

Type: Stockshots   Reference: i-077953   Duration: 00:03:08  Lieu: see shotlist
End production: 22/05/2013   First transmission: 24/05/2013
In the fight against cancer, scientists have long dreamed of a ‘magic bullet' to eliminate diseased cells without harming healthy tissue. This dream became reality when nano-capsules that deliver potent anti-cancer drugs directly to tumour sites entered clinical practice. The revolutionary method is based on breakthrough discoveries patented by Belgian-born nanotechnology pioneer Patrick Couvreur, Professor and Director of the Physical Chemistry, Pharmacotechnology and Biopharmacy Unit at Paris-Sud University in France.

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TIME DESCRIPTION DURATION
00:00:00 They protect us from UV rays and help prevent sweating. 00:00:04
00:00:04 With them, our cars stay clean longer and footballs are more resistant to abrasion. 00:00:07
00:00:11 Tiny nano-particles play a huge role in our daily lives. Nanotechnology is however also employed in the medical field, for example to treat cancer. Invisible nano-capsules transport medication directly to infected tissues in the body. 00:00:17
00:00:28 It is a revolution in cancer therapy. Patrick Couvreur is the revolutionary. Born in Belgium, the French scientist has been nominated for the European Inventor Award for his breakthrough in administering cancer medication. This is his reward for so many years of research. 00:00:19
00:00:47 IV Patrick Couvreur in French « Je ne suis pas seulement un chercheur, je suis aussi un pharmacien. Et par conséquent évidemment mon rêve le plus cher se serait de contribuer à mettre sur le marché un nouveau médicament qui soit capable en effet de traiter des maladies extrêmement graves, dont par exemple le cancer. » Translation "I am not only a researcher, but a pharmacist as well. For this reason, it has always been my dream to help create a new type of medication which can treat deadly diseases, such as cancer." 00:00:17
00:01:04 Couvreur fought for this miracle pill for over 30 years before he was able to start producing it. 00:00:07
00:01:11 He has managed to programme the nano-capsules. In his lab at the Université Paris Sud, the capsules are made in such a way that they bring medication in concentrated form directly to the effected tissue. This helps mitigate side effects. 00:00:16
00:01:27 IV Patrick Couvreur in French « Quand vous administrez un médicament anticancéreux à un organisme humain, ce médicament veut évidemment se distribuer dans tout l’organisme et bien entendu il va en résulter des effets secondaires, des effets toxiques et une efficacité qui est relativement réduite. » Translation "Normally when a drug is administered, it is distributed throughout the entire body. This causes side-effects which may lead to symptoms of poisoning, together with reduced efficacy of the drug.” 00:00:17
00:01:44 Couvreur's idea was to create an intelligent transport mechanism for cancer drugs. 00:00:07
00:01:51 IV Patrick Couvreur in French « Au niveau de la tumeur, parce qu’on va utiliser un polymère qui est biodégradable, et bien on va voir la libération du médicament, de manière spécifique au niveau du morale et donc on va voir une meilleure activité thérapeutique. » Translation "We target the tumor using a coat of polymers that reacts to the environment. So we can control the release of the drug precisely thus significantly improving the success of the treatment! " 00:00:15
00:02:06 Nano-particles are highly versatile. They make ketchup liquid. In clothing, they inhibit the growth of bacteria. 00:00:08
00:02:14 They are only visible under a microscope. The particles are less than one thousandth of a millimeter. 00:00:07
00:02:21 Patrick Couvreur and his research team believe these little helpers hold great promise and are already working on their next project. 00:00:10
00:02:31 IV Patrick Couvreur in French « Et bien nous espérons développer ces nanoparticules de gemcitabine-squalène pour arriver à traiter le cancer du pancréas, parce que vous savez que c’est une pathologie qui est extrêmement sévère, qui est mortelle et pour laquelle actuellement nous n’avons pas beaucoup de traitements, malheureusement. » Translation "With our research project, we hope that we will be able to help treat pancreatic cancer. We are all too aware of what a serious and deadly disease this is. Up until now, there have been very few treatment options available." 00:00:14
00:02:45 But for now it is all about this: the European Inventor Award. For Couvreur, his nomination is the category "research" is not just a great honor for him . . . 00:00:10
00:02:55 IV Patrick Couvreur in French « C’est important de faire connaitre également à l’opinion publique en quoi ces travaux peuvent être importants pour la société et en particulier dans notre domaine, pour traiter des maladies que l’on ne peut pas guérir a l’heure actuelle. » Translation "For us it is very important that our research gains increased awareness so that we can communicate how important it is to the patients who suffer from diseases which up till now were not treatable." 00:00:00
00:02:55 IV Patrick Couvreur in French « C’est important de faire connaitre également à l’opinion publique en quoi ces travaux peuvent être importants pour la société et en particulier dans notre domaine, pour traiter des maladies que l’on ne peut pas guérir a l’heure actuelle. » Translation "For us it is very important that our research gains increased awareness so that we can communicate how important it is to the patients who suffer from diseases which up till now were not treatable." 00:00:13
00:03:08 The Inventor Award of the European Patent Office is also known as the "Technology Oscar." It helps increase public awareness to important research. It will be presented on 28 May in Amsterdam. 00:00:00
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